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A yeast model system for functional analysis of β-catenin signaling

We have developed a novel Saccharomyces cerevisiae model system to dissect the molecular events of β-catenin (β-cat) signaling. Coexpression of mammalian β-cat with TCF4 or LEF1 results in nuclear accumulation of these proteins and a functional complex that activates reporter gene transcription from...

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Detalles Bibliográficos
Autores principales: Lee, Margaret S., D'Amour, Karen A., Papkoff, Jackie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173206/
https://www.ncbi.nlm.nih.gov/pubmed/12235124
http://dx.doi.org/10.1083/jcb.200204063