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Hyaluronan–CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9

Osteoclast (OC) precursors migrate to putative sites of bone resorption to form functionally active, multinucleated cells. The preOC FLG 29.1 cells, known to be capable of irreversibly differentiating into multinucleated OC-like cells, displayed several features of primary OCs, including expression...

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Detalles Bibliográficos
Autores principales: Spessotto, Paola, Rossi, Francesca Maria, Degan, Massimo, Di Francia, Raffaele, Perris, Roberto, Colombatti, Alfonso, Gattei, Valter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173214/
https://www.ncbi.nlm.nih.gov/pubmed/12235127
http://dx.doi.org/10.1083/jcb.200202120