T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

Tcell antigen receptor (TCR) ligation initiates tyrosine kinase activation, signaling complex assembly, and immune synapse formation. Here, we studied the kinetics and mechanics of signaling complex formation in live Jurkat leukemic T cells using signaling proteins fluorescently tagged with variants...

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Detalles Bibliográficos
Autores principales: Bunnell, Stephen C., Hong, David I., Kardon, Julia R., Yamazaki, Tetsuo, McGlade, C. Jane, Barr, Valarie A., Samelson, Lawrence E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173229/
https://www.ncbi.nlm.nih.gov/pubmed/12356870
http://dx.doi.org/10.1083/jcb.200203043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173229/
https://www.ncbi.nlm.nih.gov/pubmed/12356870
http://dx.doi.org/10.1083/jcb.200203043

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