Cargando…

T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

Tcell antigen receptor (TCR) ligation initiates tyrosine kinase activation, signaling complex assembly, and immune synapse formation. Here, we studied the kinetics and mechanics of signaling complex formation in live Jurkat leukemic T cells using signaling proteins fluorescently tagged with variants...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bunnell, Stephen C., Hong, David I., Kardon, Julia R., Yamazaki, Tetsuo, McGlade, C. Jane, Barr, Valarie A., Samelson, Lawrence E.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173229/ https://www.ncbi.nlm.nih.gov/pubmed/12356870 http://dx.doi.org/10.1083/jcb.200203043

Ejemplares similares

ZAP-70 Association with T Cell Receptor ζ (TCRζ): Fluorescence Imaging of Dynamic Changes upon Cellular Stimulation
por: Sloan-Lancaster, Joanne, et al.
Publicado: (1998)

madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy
por: Yi, Jason, et al.
Publicado: (2016)

Cluster analysis of protein array results via similarity of Gene Ontology annotation
por: Wolting, Cheryl, et al.
Publicado: (2006)

Almost a Legend – John Fry, Leading Reformer of General Practice
por: McGlade, Kieran
Publicado: (2008)

In vivo functional mapping of the conserved protein domains within murine Themis1
por: Zvezdova, Ekaterina, et al.
Publicado: (2014)

Hierarchical nanostructure and synergy of multimolecular signalling complexes
por: Sherman, Eilon, et al.
Publicado: (2016)

Safety and Toxicology of Cannabinoids
por: Sachs, Jane, et al.
Publicado: (2015)

Apical, Lateral, and Basal Polarization Cues Contribute to the Development of the Follicular Epithelium during Drosophila Oogenesis
por: Tanentzapf, Guy, et al.
Publicado: (2000)

Can education alter attitudes, behaviour and knowledge about organ donation? A pretest–post-test study
por: McGlade, Donal, et al.
Publicado: (2013)

The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8(+) T cells
por: Guittard, Geoffrey, et al.
Publicado: (2018)

Infographics: Healthcare Communication for the Digital Age
por: McCrorie, AD, et al.
Publicado: (2016)

Timed Regulation of 3BP2 Induction Is Critical for Sustaining CD8(+) T Cell Expansion and Differentiation
por: Dimitriou, Ioannis D., et al.
Publicado: (2018)

The Exploitation of Evolving Resources
por: Stokes, Kevin, et al.
Publicado: (1993)

Current State of Non-wearable Sensor Technologies for Monitoring Activity Patterns to Detect Symptoms of Mild Cognitive Impairment to Alzheimer's Disease
por: Narasimhan, Rajaram, et al.
Publicado: (2021)

Attitudes Underlying Corneal Donation in a Group of Trainee Allied Health Professionals
por: McGlade, Donal, et al.
Publicado: (2012)

Pro-Donation Behaviours of Nursing Students from the Four Countries of the UK
por: McGlade, Donal, et al.
Publicado: (2014)

Sex differences in orbitofrontal connectivity in male and female veterans with TBI
por: McGlade, Erin, et al.
Publicado: (2015)

Chronic Stress in Adolescents and Its Neurobiological and Psychopathological Consequences: An RDoC Perspective
por: Sheth, Chandni, et al.
Publicado: (2017)

Progesterone and Inflammatory Response in the Oviduct during Physiological and Pathological Conditions
por: McGlade, Emily A., et al.
Publicado: (2022)

Content and discontent: a qualitative exploration of obstacles to elearning engagement in medical students
por: Reid, Helen J., et al.
Publicado: (2016)

Online health information – what the newspapers tell their readers: a systematic content analysis
por: McCaw, Brian A, et al.
Publicado: (2014)

SLAP Is a Negative Regulator of FcεRI Receptor-Mediated Signaling and Allergic Response
por: Sharma, Namit, et al.
Publicado: (2019)

Regional and temporal variations in organ donation across the UK (secondary analyses of databases)
por: McGlade, Donal, et al.
Publicado: (2011)

Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
por: Sušac, Lukas, et al.
Publicado: (2022)

Biochemical and Computational Analysis Of LNX1 Interacting Proteins
por: Wolting, Cheryl D., et al.
Publicado: (2011)

Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia
por: Gillis, LC, et al.
Publicado: (2013)

The Effect of Surrounding Vegetation on Basal Stem Measurements Acquired Using Low-Cost Depth Sensors in Urban and Native Forest Environments
por: McGlade, James, et al.
Publicado: (2023)

Characterization of signaling complexes at the T-cell antigen receptor
por: Samelson, L
Publicado: (2003)

TCR microclusters form spatially segregated domains and sequentially assemble in calcium-dependent kinetic steps
por: Yi, Jason, et al.
Publicado: (2019)

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins
por: Dho, Sascha E., et al.
Publicado: (2019)

Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2
por: HUGHES, C E, et al.
Publicado: (2008)

Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations
por: Conibear, Anne C., et al.
Publicado: (2019)

Sortase‐Mediated Multi‐Fragment Assemblies by Ligation Site Switching
por: Bierlmeier, Jan, et al.
Publicado: (2021)

Template-Free Assembly of Functional RNAs by Loop-Closing Ligation
por: Wu, Long-Fei, et al.
Publicado: (2022)

Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation
por: Zhu, Jinfang, et al.
Publicado: (2000)

Overweight/Obesity-related microstructural alterations of the fimbria-fornix in the ABCD study: The role of aerobic physical activity
por: Ma, Jiyoung, et al.
Publicado: (2023)

A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas
por: Agnihotri, Sameer, et al.
Publicado: (2011)

Genome assembly with in vitro proximity ligation data and whole-genome triplication in lettuce
por: Reyes-Chin-Wo, Sebastian, et al.
Publicado: (2017)

Lagrangian transport in geophysical jets and waves: the dynamical systems approach
por: Samelson, R M, et al.
Publicado: (2006)

Toward Understanding the Conformational Dynamics of RNA Ligation
por: Swift, Robert V., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_g27bakv5vvrbi78nq3v443b7iu