Cargando…

TGFβ receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

Transforming growth factor (TGF)β is an important physiological regulator of cellular growth and differentiation. It activates a receptor threonine/serine kinase that phosphorylates the transcription factor Smad2, which then translocates into the nucleus to trigger specific transcriptional events. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Hayes, Susan, Chawla, Anil, Corvera, Silvia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173232/
https://www.ncbi.nlm.nih.gov/pubmed/12356868
http://dx.doi.org/10.1083/jcb.200204088