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TGFβ receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2
Transforming growth factor (TGF)β is an important physiological regulator of cellular growth and differentiation. It activates a receptor threonine/serine kinase that phosphorylates the transcription factor Smad2, which then translocates into the nucleus to trigger specific transcriptional events. H...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173232/ https://www.ncbi.nlm.nih.gov/pubmed/12356868 http://dx.doi.org/10.1083/jcb.200204088 |