A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65

The signals involved in axonal trafficking and presynaptic clustering are poorly defined. Here we show that targeting of the γ-aminobutyric acid–synthesizing enzyme glutamate decarboxylase 65 (GAD65) to presynaptic clusters is mediated by its palmitoylated 60-aa NH(2)-terminal domain and that this r...

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Detalles Bibliográficos
Autores principales: Kanaani, Jamil, El-Husseini, Alaa El-Din, Aguilera-Moreno, Andrea, Diacovo, Julia M., Bredt, David S., Baekkeskov, Steinunn
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173248/
https://www.ncbi.nlm.nih.gov/pubmed/12356867
http://dx.doi.org/10.1083/jcb.200205053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173248/
https://www.ncbi.nlm.nih.gov/pubmed/12356867
http://dx.doi.org/10.1083/jcb.200205053

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