The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance

Approximately 10% of the photoreceptor outer segment (OS) is turned over each day, requiring large amounts of lipid and protein to be moved from the inner segment to the OS. Defects in intraphotoreceptor transport can lead to retinal degeneration and blindness. The transport mechanisms are unknown,...

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Detalles Bibliográficos
Autores principales: Pazour, Gregory J., Baker, Sheila A., Deane, James A., Cole, Douglas G., Dickert, Bethany L., Rosenbaum, Joel L., Witman, George B., Besharse, Joseph C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173265/
https://www.ncbi.nlm.nih.gov/pubmed/11916979
http://dx.doi.org/10.1083/jcb.200107108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173265/
https://www.ncbi.nlm.nih.gov/pubmed/11916979
http://dx.doi.org/10.1083/jcb.200107108

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