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A cycle of Vam7p release from and PtdIns 3-P–dependent rebinding to the yeast vacuole is required for homotypic vacuole fusion

Vacuole fusion requires a coordinated cascade of priming, docking, and fusion. SNARE proteins have been implicated in the fusion itself, although their precise role in the cascade remains unclear. We now report that the vacuolar SNAP-23 homologue Vam7p is a mobile element of the SNARE complex, which...

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Detalles Bibliográficos
Autores principales: Boeddinghaus, Christine, Merz, Alexey J., Laage, Rico, Ungermann, Christian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173272/
https://www.ncbi.nlm.nih.gov/pubmed/11916982
http://dx.doi.org/10.1083/jcb.200112098