Interactions of thrombospondins with α4β1 integrin and CD47 differentially modulate T cell behavior

Thrombospondin (TSP)-1 has been reported to modulate T cell behavior both positively and negatively. We found that these opposing responses arise from interactions of TSP1 with two different T cell receptors. The integrin α4β1 recognizes an LDVP sequence in the NH(2)-terminal domain of TSP1 and was...

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Detalles Bibliográficos
Autores principales: Li, Zhuqing, Calzada, Maria J., Sipes, John M., Cashel, Jo Anne, Krutzsch, Henry C., Annis, Douglas S., Mosher, Deane F., Roberts, David D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173289/
https://www.ncbi.nlm.nih.gov/pubmed/11980922
http://dx.doi.org/10.1083/jcb.200109098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173289/
https://www.ncbi.nlm.nih.gov/pubmed/11980922
http://dx.doi.org/10.1083/jcb.200109098

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