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Interactions of thrombospondins with α4β1 integrin and CD47 differentially modulate T cell behavior
Thrombospondin (TSP)-1 has been reported to modulate T cell behavior both positively and negatively. We found that these opposing responses arise from interactions of TSP1 with two different T cell receptors. The integrin α4β1 recognizes an LDVP sequence in the NH(2)-terminal domain of TSP1 and was...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173289/ https://www.ncbi.nlm.nih.gov/pubmed/11980922 http://dx.doi.org/10.1083/jcb.200109098 |