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Dislocation and degradation from the ER are regulated by cytosolic stress
Akey step in ER-associated degradation (ERAD) is dislocation of the substrate protein from the ER into the cytosol to gain access to the proteasome. Very little is known about how this process is regulated, especially in the case of polytopic proteins. Using pulse-chase analysis combined with subcel...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173298/ https://www.ncbi.nlm.nih.gov/pubmed/11980915 http://dx.doi.org/10.1083/jcb.200111045 |