Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension

The nonreceptor tyrosine kinase encoded by the c-Abl gene has the unique feature of an F-actin binding domain (FABD). Purified c-Abl tyrosine kinase is inhibited by F-actin, and this inhibition can be relieved through mutation of its FABD. The c-Abl kinase is activated by physiological signals that...

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Detalles Bibliográficos
Autores principales: Woodring, Pamela J., Litwack, E. David, O'Leary, Dennis D.M., Lucero, Ginger R., Wang, Jean Y.J., Hunter, Tony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173320/
https://www.ncbi.nlm.nih.gov/pubmed/11864995
http://dx.doi.org/10.1083/jcb.200110014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173320/
https://www.ncbi.nlm.nih.gov/pubmed/11864995
http://dx.doi.org/10.1083/jcb.200110014

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