Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis

The mammalian Golgi complex is comprised of a ribbon of stacked cisternal membranes often located in the pericentriolar region of the cell. Here, we report that during apoptosis the Golgi ribbon is fragmented into dispersed clusters of tubulo-vesicular membranes. We have found that fragmentation is...

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Detalles Bibliográficos
Autores principales: Lane, Jon D., Lucocq, John, Pryde, James, Barr, Francis A., Woodman, Philip G., Allan, Victoria J., Lowe, Martin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173349/
https://www.ncbi.nlm.nih.gov/pubmed/11815631
http://dx.doi.org/10.1083/jcb.200110007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173349/
https://www.ncbi.nlm.nih.gov/pubmed/11815631
http://dx.doi.org/10.1083/jcb.200110007

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