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Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis
The mammalian Golgi complex is comprised of a ribbon of stacked cisternal membranes often located in the pericentriolar region of the cell. Here, we report that during apoptosis the Golgi ribbon is fragmented into dispersed clusters of tubulo-vesicular membranes. We have found that fragmentation is...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173349/ https://www.ncbi.nlm.nih.gov/pubmed/11815631 http://dx.doi.org/10.1083/jcb.200110007 |