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Tyrosine-phosphorylated and nonphosphorylated isoforms of α-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions

α-Dystrobrevin (DB), a cytoplasmic component of the dystrophin–glycoprotein complex, is found throughout the sarcolemma of muscle cells. Mice lacking αDB exhibit muscular dystrophy, defects in maturation of neuromuscular junctions (NMJs) and, as shown here, abnormal myotendinous junctions (MTJs). In...

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Detalles Bibliográficos
Autores principales: Grady, R. Mark, Akaaboune, Mohammed, Cohen, Alexander L., Maimone, Margaret M., Lichtman, Jeff W., Sanes, Joshua R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173352/
https://www.ncbi.nlm.nih.gov/pubmed/12604589
http://dx.doi.org/10.1083/jcb.200209045