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Tyrosine-phosphorylated and nonphosphorylated isoforms of α-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions
α-Dystrobrevin (DB), a cytoplasmic component of the dystrophin–glycoprotein complex, is found throughout the sarcolemma of muscle cells. Mice lacking αDB exhibit muscular dystrophy, defects in maturation of neuromuscular junctions (NMJs) and, as shown here, abnormal myotendinous junctions (MTJs). In...
Autores principales: | Grady, R. Mark, Akaaboune, Mohammed, Cohen, Alexander L., Maimone, Margaret M., Lichtman, Jeff W., Sanes, Joshua R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173352/ https://www.ncbi.nlm.nih.gov/pubmed/12604589 http://dx.doi.org/10.1083/jcb.200209045 |
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