Identification of a tight junction–associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability

Rho family GTPases are important regulators of epithelial tight junctions (TJs); however, little is known about how the GTPases themselves are controlled during TJ assembly and function. We have identified and cloned a canine guanine nucleotide exchange factor (GEF) of the Dbl family of proto-oncoge...

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Detalles Bibliográficos
Autores principales: Benais-Pont, Gaëlle, Punn, Anu, Flores-Maldonado, Catalina, Eckert, Judith, Raposo, Graça, Fleming, Tom P., Cereijido, Marcelino, Balda, Maria S., Matter, Karl
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173357/
https://www.ncbi.nlm.nih.gov/pubmed/12604587
http://dx.doi.org/10.1083/jcb.200211047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173357/
https://www.ncbi.nlm.nih.gov/pubmed/12604587
http://dx.doi.org/10.1083/jcb.200211047

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