Differential regulation of cell motility and invasion by FAK

Cell migration and invasion are fundamental components of tumor cell metastasis. Increased focal adhesion kinase (FAK) expression and tyrosine phosphorylation are connected with elevated tumorigenesis. Null mutation of FAK results in embryonic lethality, and FAK(−/−) fibroblasts exhibit cell migrati...

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Detalles Bibliográficos
Autores principales: Hsia, Datsun A., Mitra, Satyajit K., Hauck, Christof R., Streblow, Daniel N., Nelson, Jay A., Ilic, Dusko, Huang, Shuang, Li, Erguang, Nemerow, Glen R., Leng, Jay, Spencer, Kathryn S.R., Cheresh, David A., Schlaepfer, David D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173366/
https://www.ncbi.nlm.nih.gov/pubmed/12615911
http://dx.doi.org/10.1083/jcb.200212114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173366/
https://www.ncbi.nlm.nih.gov/pubmed/12615911
http://dx.doi.org/10.1083/jcb.200212114

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