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A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo
The RanGTP gradient across the interphase nuclear envelope and on the condensed mitotic chromosomes is essential for many cellular processes, including nucleocytoplasmic transport and spindle assembly. Although the chromosome-associated enzyme RCC1 is responsible for RanGTP production, the mechanism...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173367/ https://www.ncbi.nlm.nih.gov/pubmed/12604592 http://dx.doi.org/10.1083/jcb.200211004 |