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Regulation of cytochrome c oxidase activity by c-Src in osteoclasts

The function of the nonreceptor tyrosine kinase c-Src as a plasma membrane–associated molecular effector of a variety of extracellular stimuli is well known. Here, we show that c-Src is also present within mitochondria, where it phosphorylates cytochrome c oxidase (Cox). Deleting the c-src gene redu...

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Detalles Bibliográficos
Autores principales: Miyazaki, Tsuyoshi, Neff, Lynn, Tanaka, Sakae, Horne, William C., Baron, Roland
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173369/
https://www.ncbi.nlm.nih.gov/pubmed/12615910
http://dx.doi.org/10.1083/jcb.200209098