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Lamin A/C speckles mediate spatial organization of splicing factor compartments and RNA polymerase II transcription
The A-type lamins have been observed to colocalize with RNA splicing factors in speckles within the nucleus, in addition to their typical distribution at the nuclear periphery. To understand the functions of lamin speckles, the effects of transcriptional inhibitors known to modify RNA splicing facto...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173379/ https://www.ncbi.nlm.nih.gov/pubmed/12473687 http://dx.doi.org/10.1083/jcb.200204149 |