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A novel Apaf-1–independent putative caspase-2 activation complex

CVaspase activation is a key event in apoptosis execution. In stress-induced apoptosis, the mitochondrial pathway of caspase activation is believed to be of central importance. In this pathway, cytochrome c released from mitochondria facilitates the formation of an Apaf-1 apoptosome that recruits an...

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Detalles Bibliográficos
Autores principales: Read, Stuart H., Baliga, Belinda C., Ekert, Paul G., Vaux, David L., Kumar, Sharad
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173397/
https://www.ncbi.nlm.nih.gov/pubmed/12460989
http://dx.doi.org/10.1083/jcb.200209004