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Building an efficient factory: where is pre-rRNA synthesized in the nucleolus?

The subnucleolar structure that is involved in rDNA transcription has been controversial. A report by Koberna et al. (2002)(this issue, page 743) adds significant weight toward the idea that dense fibrillar components (DFCs) and fibrillar center (FC)/DFC borders are the sites of pre-rRNA synthesis.

Detalles Bibliográficos
Autor principal: Huang, Sui
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173404/
https://www.ncbi.nlm.nih.gov/pubmed/12034767
http://dx.doi.org/10.1083/jcb.200204159