LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics

The small GTPase RhoA controls activity of serum response factor (SRF) by inducing changes in actin dynamics. We show that in PC12 cells, activation of SRF after serum stimulation is RhoA dependent, requiring both actin polymerization and the Rho kinase (ROCK)–LIM kinase (LIMK)–cofilin signaling pat...

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Detalles Bibliográficos
Autores principales: Geneste, Olivier, Copeland, John W., Treisman, Richard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173419/
https://www.ncbi.nlm.nih.gov/pubmed/12034774
http://dx.doi.org/10.1083/jcb.200203126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173419/
https://www.ncbi.nlm.nih.gov/pubmed/12034774
http://dx.doi.org/10.1083/jcb.200203126

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