Cargando…

LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics

The small GTPase RhoA controls activity of serum response factor (SRF) by inducing changes in actin dynamics. We show that in PC12 cells, activation of SRF after serum stimulation is RhoA dependent, requiring both actin polymerization and the Rho kinase (ROCK)–LIM kinase (LIMK)–cofilin signaling pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geneste, Olivier, Copeland, John W., Treisman, Richard
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173419/ https://www.ncbi.nlm.nih.gov/pubmed/12034774 http://dx.doi.org/10.1083/jcb.200203126

Ejemplares similares

Enabled Negatively Regulates Diaphanous-Driven Actin Dynamics In Vitro and In Vivo
por: Bilancia, Colleen G., et al.
Publicado: (2014)

Formin’ cellular structures: Physiological roles of Diaphanous (Dia) in actin dynamics
por: Bogdan, Sven, et al.
Publicado: (2014)

The Formin Diaphanous Regulates Myoblast Fusion through Actin Polymerization and Arp2/3 Regulation
por: Deng, Su, et al.
Publicado: (2015)

Cofilin Phosphorylation and Actin Cytoskeletal Dynamics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2
por: Sumi, Tomoyuki, et al.
Publicado: (1999)

The actin regulators Enabled and Diaphanous direct distinct protrusive behaviors in different tissues during Drosophila development
por: Nowotarski, Stephanie H., et al.
Publicado: (2014)

Involvement of LIM kinase 1 in actin polarization in human CD4 T cells
por: Xu, Xuehua, et al.
Publicado: (2012)

Flightless-I (Fli-I) Regulates the Actin Assembly Activity of Diaphanous-related Formins (DRFs) Daam1 and mDia1 in Cooperation with Active Rho GTPase
por: Higashi, Tomohito, et al.
Publicado: (2010)

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes
por: Ishaq, Mohammad, et al.
Publicado: (2011)

ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells
por: Kapur, Reuben, et al.
Publicado: (2016)

Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLα and mDia1
por: Seth, Abhinav, et al.
Publicado: (2006)

Palmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity
por: George, Joju, et al.
Publicado: (2015)

Correction: LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes
por: Ishaq, Mohammad, et al.
Publicado: (2012)

Helical rotation of the diaphanous-related formin mDia1 generates actin filaments resistant to cofilin
por: Mizuno, Hiroaki, et al.
Publicado: (2018)

LIM kinase regulation of cytoskeletal dynamics is required for salivary gland branching morphogenesis
por: Ray, Shayoni, et al.
Publicado: (2014)

LIM kinases: cofilin and beyond
por: Prunier, Chloé, et al.
Publicado: (2017)

LIM Kinases in Osteosarcoma Development
por: Brion, Régis, et al.
Publicado: (2021)

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts
por: Esnault, Cyril, et al.
Publicado: (2014)

Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL
por: Mouilleron, Stephane, et al.
Publicado: (2008)

LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain
por: Smith, Mark A., et al.
Publicado: (2013)

Targeting LIM kinase in cancer and neurofibromatosis
por: Rak, Roni, et al.
Publicado: (2014)

Diaphanous formin mDia2 regulates CENP-A levels at centromeres
por: Liu, Chenshu, et al.
Publicado: (2016)

Apical targeting of the formin Diaphanous in Drosophila tubular epithelia
por: Rousso, Tal, et al.
Publicado: (2013)

Role of Cytoskeletal Diaphanous-Related Formins in Hearing Loss
por: Chiereghin, Chiara, et al.
Publicado: (2022)

Targeting LIM kinases in taxane resistant tumors
por: Prunier, Chloé, et al.
Publicado: (2016)

The Role of LIM Kinase in the Male Urogenital System
por: Park, Juhyun, et al.
Publicado: (2021)

LIM Kinases: From Molecular to Pathological Features
por: Bénédetti, Hélène, et al.
Publicado: (2023)

Characterization of Diaphanous-related formin FMNL2 in human tissues
por: Gardberg, Maria, et al.
Publicado: (2010)

Diaphanous gene mutation affects spiral cleavage and chirality in snails
por: Kuroda, Reiko, et al.
Publicado: (2016)

Cleavage and activation of LIM kinase 1 as a novel mechanism for calpain 2-mediated regulation of nuclear dynamics
por: Rodríguez-Fernández, L., et al.
Publicado: (2021)

Mammalian Diaphanous-Related Formin 1 Regulates GSK3β-Dependent Microtubule Dynamics Required for T Cell Migratory Polarization
por: Dong, Baoxia, et al.
Publicado: (2013)

Diaphanous-related formin subfamily: Novel prognostic biomarkers and tumor microenvironment regulators for pancreatic adenocarcinoma
por: Zhang, Bixi, et al.
Publicado: (2022)

LIM kinases in synaptic plasticity and their potential as therapeutic targets
por: Halász, Éva, et al.
Publicado: (2020)

LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases
por: Ben Zablah, Youssif, et al.
Publicado: (2021)

The complete mitochondrial genome of the firefly, Diaphanes citrinus (Olivier), (coleoptera: Lampyridae)
por: Yang, Zhuo, et al.
Publicado: (2019)

Home-Care Workers’ Representations of Their Role and Competences: A Diaphanous Profession
por: Gazzaroli, Diletta, et al.
Publicado: (2020)

Cooperation of LIM domain‐binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia
por: Ohnishi, Tetsuo, et al.
Publicado: (2021)

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A
por: Pawłowski, Rafał, et al.
Publicado: (2010)

The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells
por: Becker, Kathryn N., et al.
Publicado: (2022)

Rho-kinase regulates tissue morphogenesis via non-muscle myosin and LIM-kinase during Drosophila development
por: Verdier, Valerie, et al.
Publicado: (2006)

Downregulation of LIM kinase 1 suppresses ocular inflammation and fibrosis
por: Gorovoy, Matvey, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_me5dio1td0vtpkat2m5ok196ad