H2AX regulates meiotic telomere clustering

The histone H2A variant H2AX is phosphorylated in response to DNA double-strand breaks originating from diverse origins, including dysfunctional telomeres. Here, we show that normal mitotic telomere maintenance does not require H2AX. Moreover, H2AX is dispensable for the chromosome fusions arising f...

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Detalles Bibliográficos
Autores principales: Fernandez-Capetillo, Oscar, Liebe, Bodo, Scherthan, Harry, Nussenzweig, André
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173436/
https://www.ncbi.nlm.nih.gov/pubmed/14530383
http://dx.doi.org/10.1083/jcb.200305124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173436/
https://www.ncbi.nlm.nih.gov/pubmed/14530383
http://dx.doi.org/10.1083/jcb.200305124

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