Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact

The integrin α3β1 mediates cellular adhesion to the matrix ligand laminin-5. A second integrin ligand, the urokinase receptor (uPAR), associates with α3β1 via a surface loop within the α3 β-propeller (residues 242–246) but outside the laminin binding region, suggesting that uPAR–integrin interaction...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Tom, Clifford C., Kugler, Matthias C., Ching, Tsui-Ting, Kreidberg, Jordan A., Wei, Ying, Chapman, Harold A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173444/
https://www.ncbi.nlm.nih.gov/pubmed/14557254
http://dx.doi.org/10.1083/jcb.200304065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173444/
https://www.ncbi.nlm.nih.gov/pubmed/14557254
http://dx.doi.org/10.1083/jcb.200304065

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