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CD46 is phosphorylated at tyrosine 354 upon infection of epithelial cells by Neisseria gonorrhoeae

The Neisseria type IV pilus promotes bacterial adhesion to host cells. The pilus binds CD46, a complement-regulatory glycoprotein present on nucleated human cells (Källström et al., 1997). CD46 mutants with truncated cytoplasmic tails fail to support bacterial adhesion (Källström et al., 2001), sugg...

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Detalles Bibliográficos
Autores principales: Lee, Shaun W., Bonnah, Robert A., Higashi, Dustin L., Atkinson, John P., Milgram, Sharon L., So, Magdalene
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173477/
https://www.ncbi.nlm.nih.gov/pubmed/11901164
http://dx.doi.org/10.1083/jcb.200109005