Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function

Mutations in the human LIS1 gene cause type I lissencephaly, a severe brain developmental disease involving gross disorganization of cortical neurons. In lower eukaryotes, LIS1 participates in cytoplasmic dynein-mediated nuclear migration. We previously reported that mammalian LIS1 functions in cell...

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Detalles Bibliográficos
Autores principales: Tai, Chin-Yin, Dujardin, Denis L., Faulkner, Nicole E., Vallee, Richard B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173479/
https://www.ncbi.nlm.nih.gov/pubmed/11889140
http://dx.doi.org/10.1083/jcb.200109046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173479/
https://www.ncbi.nlm.nih.gov/pubmed/11889140
http://dx.doi.org/10.1083/jcb.200109046

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