Cargando…
Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function
Mutations in the human LIS1 gene cause type I lissencephaly, a severe brain developmental disease involving gross disorganization of cortical neurons. In lower eukaryotes, LIS1 participates in cytoplasmic dynein-mediated nuclear migration. We previously reported that mammalian LIS1 functions in cell...
Autores principales: | Tai, Chin-Yin, Dujardin, Denis L., Faulkner, Nicole E., Vallee, Richard B. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173479/ https://www.ncbi.nlm.nih.gov/pubmed/11889140 http://dx.doi.org/10.1083/jcb.200109046 |
Ejemplares similares
-
Narcissistic CLIP-170 also attracts dynactin
por: LeBrasseur, Nicole
Publicado: (2004) -
Lis1 activates dynein motility by modulating its pairing with dynactin
por: Elshenawy, Mohamed M., et al.
Publicado: (2020) -
ZW10 Helps Recruit Dynactin and Dynein to the Kinetochore
por: Starr, Daniel A., et al.
Publicado: (1998) -
Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis
por: Wang, Shusheng, et al.
Publicado: (2013) -
LIS1 Regulates Osteoclast Formation and Function through Its Interactions with Dynein/Dynactin and Plekhm1
por: Ye, Shiqiao, et al.
Publicado: (2011)