DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals

Death-associated protein kinase (DAP-kinase) is a calcium/calmodulin-dependent serine/threonine kinase, and participates in various apoptosis systems. However, its apoptosis-promoting mechanism is poorly understood. Here, we demonstrate that DAP-kinase suppresses integrin-mediated cell adhesion and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Won-Jing, Kuo, Jean-Cheng, Yao, Chung-Chen, Chen, Ruey-Hwa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173490/
https://www.ncbi.nlm.nih.gov/pubmed/12370243
http://dx.doi.org/10.1083/jcb.200204050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173490/
https://www.ncbi.nlm.nih.gov/pubmed/12370243
http://dx.doi.org/10.1083/jcb.200204050

Ejemplares similares