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DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals

Death-associated protein kinase (DAP-kinase) is a calcium/calmodulin-dependent serine/threonine kinase, and participates in various apoptosis systems. However, its apoptosis-promoting mechanism is poorly understood. Here, we demonstrate that DAP-kinase suppresses integrin-mediated cell adhesion and...

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Detalles Bibliográficos
Autores principales:	Wang, Won-Jing, Kuo, Jean-Cheng, Yao, Chung-Chen, Chen, Ruey-Hwa
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173490/ https://www.ncbi.nlm.nih.gov/pubmed/12370243 http://dx.doi.org/10.1083/jcb.200204050

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