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ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat

The role of GTPase-activating protein (GAP) that deactivates ADP-ribosylation factor 1 (ARF1) during the formation of coat protein I (COPI) vesicles has been unclear. GAP is originally thought to antagonize vesicle formation by triggering uncoating, but later studies suggest that GAP promotes cargo...

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Detalles Bibliográficos
Autores principales: Yang, Jia-Shu, Lee, Stella Y., Gao, Minggeng, Bourgoin, Sylvain, Randazzo, Paul A., Premont, Richard T., Hsu, Victor W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173491/
https://www.ncbi.nlm.nih.gov/pubmed/12379802
http://dx.doi.org/10.1083/jcb.200206015