Calcium-regulated exocytosis of dense-core vesicles requires the activation of ADP-ribosylation factor (ARF)6 by ARF nucleotide binding site opener at the plasma membrane

The ADP ribosylation factor (ARF) GTP binding proteins are believed to mediate cytoskeletal remodeling and vesicular trafficking along the secretory pathway. Here we show that ARF6 is specifically associated with dense-core secretory granules in neuroendocrine PC12 cells. Stimulation with a secretag...

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Detalles Bibliográficos
Autores principales: Vitale, Nicolas, Chasserot-Golaz, Sylvette, Bailly, Yannick, Morinaga, Naoko, Frohman, Michael A., Bader, Marie-France
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173505/
https://www.ncbi.nlm.nih.gov/pubmed/12379803
http://dx.doi.org/10.1083/jcb.200203027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173505/
https://www.ncbi.nlm.nih.gov/pubmed/12379803
http://dx.doi.org/10.1083/jcb.200203027

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