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The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains

Most epithelial cells contain two AP-1 clathrin adaptor complexes. AP-1A is ubiquitously expressed and involved in transport between the TGN and endosomes. AP-1B is expressed only in epithelia and mediates the polarized targeting of membrane proteins to the basolateral surface. Both AP-1 complexes a...

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Detalles Bibliográficos
Autores principales: Fölsch, Heike, Pypaert, Marc, Maday, Sandra, Pelletier, Laurence, Mellman, Ira
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173537/
https://www.ncbi.nlm.nih.gov/pubmed/14581457
http://dx.doi.org/10.1083/jcb.200309020