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The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains
Most epithelial cells contain two AP-1 clathrin adaptor complexes. AP-1A is ubiquitously expressed and involved in transport between the TGN and endosomes. AP-1B is expressed only in epithelia and mediates the polarized targeting of membrane proteins to the basolateral surface. Both AP-1 complexes a...
Autores principales: | Fölsch, Heike, Pypaert, Marc, Maday, Sandra, Pelletier, Laurence, Mellman, Ira |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173537/ https://www.ncbi.nlm.nih.gov/pubmed/14581457 http://dx.doi.org/10.1083/jcb.200309020 |
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