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Conditional disruption of β1 integrin in Schwann cells impedes interactions with axons

In dystrophic mice, a model of merosin-deficient congenital muscular dystrophy, laminin-2 mutations produce peripheral nerve dysmyelination and render Schwann cells unable to sort bundles of axons. The laminin receptor and the mechanism through which dysmyelination and impaired sorting occur are unk...

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Detalles Bibliográficos
Autores principales: Feltri, M. Laura, Porta, Diana Graus, Previtali, Stefano C., Nodari, Alessandro, Migliavacca, Barbara, Cassetti, Arianna, Littlewood-Evans, Amanda, Reichardt, Louis F., Messing, Albee, Quattrini, Angelo, Mueller, Ulrich, Wrabetz, Lawrence
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173589/
https://www.ncbi.nlm.nih.gov/pubmed/11777940
http://dx.doi.org/10.1083/jcb.200109021