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The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gβγ
PLIC-1, a newly described ubiquitin-related protein, inhibited both Jurkat migration toward SDF-1α and A431 wound healing, but the closely related PLIC-2 did not. PLIC-1 prevented the SDF-1α–induced activation of phospholipase C, decreased ligand-induced internalization of SDF-1α receptor CXCR4 and...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173627/ https://www.ncbi.nlm.nih.gov/pubmed/14662753 http://dx.doi.org/10.1083/jcb.200307155 |