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Ca(2+) influx–independent synaptic potentiation mediated by mitochondrial Na(+)-Ca(2+) exchanger and protein kinase C

Activity-dependent modulation of synaptic transmission is an essential mechanism underlying many brain functions. Here we report an unusual form of synaptic modulation that depends on Na(+) influx and mitochondrial Na(+)-Ca(2+) exchanger, but not on Ca(2+) influx. In Ca(2+)-free medium, tetanic stim...

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Detalles Bibliográficos
Autores principales: Yang, Feng, He, Xiang-ping, Russell, James, Lu, Bai
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173636/
https://www.ncbi.nlm.nih.gov/pubmed/14610054
http://dx.doi.org/10.1083/jcb.200307027