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SUMO-2/3 regulates topoisomerase II in mitosis

We have analyzed the abundance of SUMO-conjugated species during the cell cycle in Xenopus egg extracts. The predominant SUMO conjugation products associated with mitotic chromosomes arose from SUMO conjugation of topoisomerase II. Topoisomerase II was modified exclusively by SUMO-2/3 during mitosis...

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Detalles Bibliográficos
Autores principales: Azuma, Yoshiaki, Arnaoutov, Alexei, Dasso, Mary
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173648/
https://www.ncbi.nlm.nih.gov/pubmed/14597774
http://dx.doi.org/10.1083/jcb.200304088