Cargando…

Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA

Using conditional gene targeting in mice, we show that BMP receptor IA is essential for the differentiation of progenitor cells of the inner root sheath and hair shaft. Without BMPRIA activation, GATA-3 is down-regulated and its regulated control of IRS differentiation is compromised. In contrast, L...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobielak, Krzysztof, Pasolli, H. Amalia, Alonso, Laura, Polak, Lisa, Fuchs, Elaine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173651/
https://www.ncbi.nlm.nih.gov/pubmed/14610062
http://dx.doi.org/10.1083/jcb.200309042