Smn, the spinal muscular atrophy–determining gene product, modulates axon growth and localization of β-actin mRNA in growth cones of motoneurons

Spinal muscular atrophy (SMA), a common autosomal recessive form of motoneuron disease in infants and young adults, is caused by mutations in the survival motoneuron 1 (SMN1) gene. The corresponding gene product is part of a multiprotein complex involved in the assembly of spliceosomal small nuclear...

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Detalles Bibliográficos
Autores principales: Rossoll, Wilfried, Jablonka, Sibylle, Andreassi, Catia, Kröning, Ann-Kathrin, Karle, Kathrin, Monani, Umrao R., Sendtner, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173668/
https://www.ncbi.nlm.nih.gov/pubmed/14623865
http://dx.doi.org/10.1083/jcb.200304128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173668/
https://www.ncbi.nlm.nih.gov/pubmed/14623865
http://dx.doi.org/10.1083/jcb.200304128

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