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Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels

A tumor-homing peptide, F3, selectively binds to endothelial cells in tumor blood vessels and to tumor cells. Here, we show that the cell surface molecule recognized by F3 is nucleolin. Nucleolin specifically bound to an F3 peptide affinity matrix from extracts of cultured breast carcinoma cells. An...

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Detalles Bibliográficos
Autores principales: Christian, Sven, Pilch, Jan, Akerman, Maria E., Porkka, Kimmo, Laakkonen, Pirjo, Ruoslahti, Erkki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173679/
https://www.ncbi.nlm.nih.gov/pubmed/14638862
http://dx.doi.org/10.1083/jcb.200304132