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Signal-dependent distribution of cell surface P-selectin in clathrin-coated pits affects leukocyte rolling under flow

Flowing leukocytes roll on P-selectin that is mobilized from secretory granules to the surfaces of endothelial cells after stimulation with histamine or thrombin. Before it is internalized, P-selectin clusters in clathrin-coated pits, which enhances its ability to support leukocyte rolling. We found...

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Detalles Bibliográficos
Autores principales: Setiadi, Hendra, McEver, Rodger P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173709/
https://www.ncbi.nlm.nih.gov/pubmed/14676308
http://dx.doi.org/10.1083/jcb.200307178