Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death

Caspase-directed apoptosis usually fragments cells, releasing nonfunctional, prothrombogenic, membrane-bound apoptotic bodies marked for rapid engulfment by macrophages. Blood platelets are functional anucleate cells generated by specialized fragmentation of their progenitors, megakaryocytes (MKs),...

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Detalles Bibliográficos
Autores principales: Clarke, Murray C.H., Savill, John, Jones, David B., Noble, Brendon S., Brown, Simon B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173731/
https://www.ncbi.nlm.nih.gov/pubmed/12591916
http://dx.doi.org/10.1083/jcb.200210111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173731/
https://www.ncbi.nlm.nih.gov/pubmed/12591916
http://dx.doi.org/10.1083/jcb.200210111

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