Cargando…
Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death
Caspase-directed apoptosis usually fragments cells, releasing nonfunctional, prothrombogenic, membrane-bound apoptotic bodies marked for rapid engulfment by macrophages. Blood platelets are functional anucleate cells generated by specialized fragmentation of their progenitors, megakaryocytes (MKs),...
Autores principales: | Clarke, Murray C.H., Savill, John, Jones, David B., Noble, Brendon S., Brown, Simon B. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173731/ https://www.ncbi.nlm.nih.gov/pubmed/12591916 http://dx.doi.org/10.1083/jcb.200210111 |
Ejemplares similares
-
The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis
por: Moujalled, Diane, et al.
Publicado: (2021) -
In vitro Generation of Megakaryocytes and Platelets
por: Liu, Huicong, et al.
Publicado: (2021) -
Blocking caspase-independent death
por: LeBrasseur, Nicole
Publicado: (2002) -
The heterogeneity of megakaryocytes and platelets and implications for ex vivo platelet generation
por: Liu, Cuicui, et al.
Publicado: (2021) -
Generation of HLA Universal Megakaryocytes and Platelets by Genetic Engineering
por: Figueiredo, Constanca, et al.
Publicado: (2021)