Cargando…

A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control

SCC4 human keratinocytes are derived from a squamous cell carcinoma of the tongue and undergo very little spontaneous differentiation. Introduction of a wild-type β1 integrin subunit into SCC4 cells stimulates differentiation, suggesting either that the cells have a defect in the integrin signaling...

Descripción completa

Detalles Bibliográficos
Autores principales: Evans, Richard D., Perkins, Vivienne C., Henry, Alistair, Stephens, Paul E., Robinson, Martyn K., Watt, Fiona M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173744/
https://www.ncbi.nlm.nih.gov/pubmed/12578911
http://dx.doi.org/10.1083/jcb.200209016