Elevated glucose inhibits VEGF-A–mediated endocardial cushion formation: modulation by PECAM-1 and MMP-2

Atrioventricular (AV) septal defects resulting from aberrant endocardial cushion (EC) formation are observed at increased rates in infants of diabetic mothers. EC formation occurs via an epithelial-mesenchymal transformation (EMT), involving transformation of endocardial cells into mesenchymal cells...

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Detalles Bibliográficos
Autores principales: Enciso, Josephine M., Gratzinger, Dita, Camenisch, Todd D., Canosa, Sandra, Pinter, Emese, Madri, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173755/
https://www.ncbi.nlm.nih.gov/pubmed/12591918
http://dx.doi.org/10.1083/jcb.200209014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173755/
https://www.ncbi.nlm.nih.gov/pubmed/12591918
http://dx.doi.org/10.1083/jcb.200209014

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