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Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae

Dicentric chromosomes undergo a breakage–fusion–bridge cycle as a consequence of having two centromeres on the same chromatid attach to opposite spindle poles in mitosis. Suppression of dicentric chromosome breakage reflects loss of kinetochore function at the kinetochore–microtubule or the kinetoch...

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Detalles Bibliográficos
Autores principales: Mythreye, Karthikeyan, Bloom, Kerry S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173759/
https://www.ncbi.nlm.nih.gov/pubmed/12642611
http://dx.doi.org/10.1083/jcb.200211116