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Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae
Dicentric chromosomes undergo a breakage–fusion–bridge cycle as a consequence of having two centromeres on the same chromatid attach to opposite spindle poles in mitosis. Suppression of dicentric chromosome breakage reflects loss of kinetochore function at the kinetochore–microtubule or the kinetoch...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173759/ https://www.ncbi.nlm.nih.gov/pubmed/12642611 http://dx.doi.org/10.1083/jcb.200211116 |